Show notes
In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity.We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health.We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others.Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness.Access the full show notes for this episode at hubermanlab.com.Thank you to our sponsorsAG1: https://drinkag1.com/hubermanMateina: https://drinkmateina.com/hubermanEight Sleep: https://www.eightsleep.com/hubermanMaui Nui: https://mauinuivenison.com/hubermanLMNT: https://drinklmnt.com/hubermanTimestamps00:00:00 Dr. Layne Norton00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui00:06:39 Science-Based Evidence, Mechanism vs. Outcome00:14:31 Meta-analysis, Methods, Evidence Quality00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data00:33:53 Sponsor: AG100:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis00:42:01 Protein Synthesis, Refractory Response; Resistance Training 00:46:05 Protein Intake, Intermittent Fasting & Training00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth01:05:34 Sponsor: LMNT01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet01:19:50 “The Norton Method”; Tool: Consistency01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest01:33:50 Mind & Body Effects, Stress; Belief Effects01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training01:50:24 Fatigue & Training to Failure, Speed, Strength Training01:59:06 Tool: Training After 50, Consistency02:09:12 Fat Cells, Diabetes, Exercise02:16:50 Metabolism & Age-Related Changes?, Appetite02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise”02:33:42 GLP-1 Agonists, Judgement & Obesity02:40:19 Sugar, Excess Calories, Body Weight02:49:16 Satiety, Sugar & Calorie Budget02:54:56 Tool: Individualization, Context & Diet Psychology02:57:22 Seed Oils, Butter, Olive Oil03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits03:13:43 Saturated Fat, Cholesterol; Seed Oils03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein03:57:00 Evidence-Based Approach04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network NewsletterDisclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices