In this episode, I discuss placebo and belief and mindset effects — all of which exert a powerful and real influence on our biology and psychology. I discuss how your beliefs and expectation that a certain outcome will occur after taking a substance (or any intervention cause genuine changes in brain and bodily function. I discuss how placebos can change neurotransmitter and hormone release, pain levels, whether the stress response is beneficial or detrimental and more. I also explain how placebo effects can work with traditional drug or behavioral treatments to help improve health outcomes and why some people are more susceptible to placebo effects. By the end of the episode, listeners will understand the placebo effect, how it works, and how beliefs and mindsets can be leveraged toward mental health, physical health, and performance goals. For show notes, including referenced articles and additional resources, please visit hubermanlab.com.Thank you to our sponsorsAG1: https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanlabWaking Up: https://wakingup.com/hubermanTimestamps

Placebo Effects

Sponsors: Eight Sleep, AeroPress & Levels

Placebo, Nocebo vs. Belief Effect, Prefrontal Cortex

Dopamine, Placebo & Parkinson’s Disease; Placebo Controls

Hormone Release & Placebo Effect, Paired Associations

Conditioning Effect & Insulin; Pavlovian Response

Sponsor: AG1

Context & Expectations; Placebo Effect & Brain

Cancer, Mind-Body Practices; Placebo Effects & Limits

Asthma, Specificity & Placebo Effects

Sponsor: InsideTracker

Nicotine & Dose-Dependent Placebo Effects

Placebo Effects vs. Belief Effects, Food & Mindset

Exercise & Belief Effects

Placebo Effect, Brain & Stress Response

Individual Variation, Genetics & Placebo Effect