In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1: https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanlabWaking Up: https://wakingup.com/hubermanMomentous: https://livemomentous.com/hubermanTimestamps

Cannabis (Marijuana)

Sponsor: LMNT

Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety

Cannabis Strains, Psychoactive Compounds: THC & CBD

Sativa vs. Indica, Stimulant vs. Relaxation Effects

Hybrid Cannabis Strains, Type 1, 2 & 3 Strains

Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)

Sponsor: AG1

THC, CBD vs. Endogenous Cannabinoids, Dependence

Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function

Biological Effects of Cannabis

Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia

Cannabis Indica & Subjective Effects, Memory, Dosage

Brain Areas Affected by THC & CBD, Side Effects

Creativity: Convergent vs. Divergent Thinking & Dopamine

Does Cannabis Increase Creativity?

Chronic Cannabis Use & Changes in Speech Patterns

Cannabis & Libido, Dopamine & Prolactin

Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility

Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences

Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development

Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance

Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis

Adolescent Cannabis Use: Brain Development & Mental Health Disorders

Cannabis & Pain Management, Divergent Effects of Cannabis