My guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health and well-being in both men and women. We discuss how to improve hormones using behavioral, nutritional, and exercise-based tools and safely and rationally approach supplementation and hormone therapies. We discuss testosterone and estrogen and how those hormones relate to fertility, mood, aging, relationships, disease pathologies, thyroid hormone, growth hormone, prolactin, dopamine and peptides that impact physical and mental health and vitality across the lifespan. The episode is rich with scientific mechanisms and tools for people to consider.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1: https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanlabWaking Up: https://wakingup.com/hubermanMomentous: https://livemomentous.com/hubermanTimestamps

Dr. Kyle Gillett, MD, Hormone Optimization

Sponsors: AG1, LMNT

Preventative Medicine & Hormone Health

The Six Pillars of Hormone Health Optimization

Diet for Hormone Health, Blood Testing

Exercise for Hormone Health

Caloric Restriction, Obesity & Testosterone

Intermittent Fasting, Growth Hormone (GH), IGF-1

Sleep Quality & Hormones

Testosterone in Women

Dihydrotestosterone (DHT), Hair Loss

DHT in Men and Women, Turmeric/Curcumin, Creatine

5-Alpha Reductase, Finasteride, Saw Palmetto

Hair loss, DHT, Creatine Monohydrate

Hair Regrowth, Male Pattern Baldness

Polycystic Ovary Syndrome (PCOS), Inositol, DIM

Oral Contraception, Perceived Attractiveness, Fertility

Testosterone & Marijuana or Alcohol

Sleep Supplement Frequency

Testosterone Supplementation & Prostate Cancer

Prostate Health, Dietary Fiber, Saw Palmetto, C-Reactive Protein

Prostate Health & Pelvic Floor, Viagra, Tadalafil

Testosterone Replacement Therapy (TRT)

Estrogen & Aromatase Inhibitors, Calcium D-Glucarate, DIM

Lifestyle Factors to Increase Testosterone/Estrogen Levels, Dietary Fats

Aromatase Supplements: Ecdysterone, Turkesterone

Tongkat Ali (Long Jack), Estrogen/Testosterone levels

Fadogia Agrestis, Luteinizing Hormone (LH), Frequency

Boron, Sex Hormone Binding Globulin (SHBG)

Human Chorionic Gonadotropin (hCG), Fertility

Prolactin & Dopamine, Pituitary Damage

Augmenting Dopamine Levels: Casein, Gluten, Vitamin E, Vitamin B6 (P5P)

L-Carnitine & Fertility, TMAO & Allicin (Garlic)

Blood Test Frequency

Long-Term Relationships & Effects on Hormones

Nesting Instincts: Prolactin, Childbirth & Relationships

Cold & Hot Exposure, Hormones & Fertility

Peptide Hormones: Insulin, Tesamorelin, Ghrelin

Growth Hormone-Releasing Peptides (GHRPs)

BPC-157 & Injury, Dosing Frequency

Uses for Melanotan

Spiritual Health Impact on Mental & Physical Health

Caffeine & Hormones