Introduction  00:00:31 Sponsors: AG1, LMNT & Waking Up  00:06:00 Fat Loss: The Key Role of Neurons  00:08:44 The First Law of Fat Loss  00:11:00 Neurons Connect To Fat! (& That Really Matters)  00:13:38 5 Pillars of Metabolism: Sleep, Essential Fatty Acids, Glutamine, Microbiome, Thyroid  00:19:20 Mindset Truly Matters: Amazing Examples of Beliefs on Fat Loss  00:23:08 Our Brain Talks To Our Fat  00:25:00 The Most Incredible & Dangerous Fat Loss Agent  00:27:28 Losing Fat Is a Two-Part Process: Mobilization and Oxidation  00:32:25 The Critical Role of Adrenaline/Epinephrine, But NOT from Adrenal Glands  00:34:45 Fidgeting & Shivering: A Powerful Science-Supported Method For Fat Loss  00:41:24 How Fidgeting Works: Promotes Epinephrine Release into Fat. “N-E-A-T”  00:44:55 Two Ways of Using Shivering To Accelerate Fat Loss  00:47:30 White, Brown & Beige Fat; & Using Cold-Induced Shiver To Burn Fat  00:50:25 How To Use Cold Properly To Stimulate Fat Loss: Succinate Release Is Key/Shiver  00:52:26 Exact Protocols: (1-5X per week); Don’t Adapt! Submerge and Exit “Sets & Reps”  00:56:15 thecoldplunge.com see “protocols” tab Cold-Shiver-Fat-Loss Tool (cost free)  00:58:03 If Fat-Loss Is Your Goal, Avoid Cold Adaptation: Remember Polar Bear Swimmers  00:58:17 Irisin: Underwhelming; Succinate Is The Real Deal  01:00:00 Brown Fat, Why Babies Can’t Shiver and Becoming a Hotter Furnace, Adding Heat  01:01:55 Ice On Back of The Neck, Cold Underpants: Not A Great Idea For Fat Loss  01:04:00 A Key Paper For the Aficionados: www.ncbi.nlm.nih.gov/pmc/articles/PMC2826518/  01:05:00 Spot Reduction: There May Be Hope After All. Targeting Specific Fat Pads.  01:09:20 Exercising For Fat Loss: What Is Best? High Intensity, Sprinting, Moderate Intensity?  01:13:30 Exercising Fasted: Does It Truly Accelerate Fat Loss/Oxidation.  01:16:30 The 90 Minute Rule: After 90 Minutes, The Fasted Exercisers Start To Burn More Fat  01:18:15 If High-Intensity Training Is Done First, The Benefits of Fasting Arrive Before 90min.  01:22:44 Post-Exercise Metabolic Increases: How To Bias This Toward Fat Oxidation  01:26:05 A Protocol For Exercise-Induced Fat Loss; Adrenalin Is The Effector  01:28:50 Supplements/Compounds For Fat Loss Part: Caffeine Fidgeting, & Caffeine Adaptation  01:34:30 Ephedrine, Fenfluramine: Removed From Market Due to Safety Concerns  01:35:22 GLP1 (Glucagon-Like Peptide 1), Yerba Mate, Guayusa Tea, Semaglutide  01:40:30 Berberine, Metformin: Glucose/Insulin Reduction, Increase Fat Oxidation: But Caution  01:41:28 Gardner Lab Results: What You Eat May Not Matter, But Adherence Is Key Tool  01:43:00 examine.com & Enter “Yerba Mate”: Lowers Heart Rate Even Though Is a Stimulant  01:44:35 Acetyl-L-Carnitine: Facilitates Fat Oxidation  01:48:00 Summary List of Tools & How Nervous System Controls Fat Loss  01:51:20 Cost Free & Other Ways To Support Our Podcast, Making Sure We See Feedback  Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices