Sally Adee is the author of We Are Electric: Inside the 200-Year Hunt for Our Body's Bioelectric Code, and What the Future Holds. Adee joins Big Technology Podcast to pull back the curtain on the body’s hidden wiring and brain-computer interfaces. We dig into how electricity drives every thought and twitch, why Neuralink’s first patient blew our minds, and what it will take to keep implants working long after the hype cycle fades. Tune in for a tour of limb-regrowing tadpoles, cancer cells that short-circuit, and the uncomfortable ethics of pleasure buttons and startup bankruptcies. We also tackle the hard numbers—electrode counts, word-per-minute Hit play and get current. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Did AI take a step back with GPT-5? 2) Is AI hype going to cool off? 3) GPT-5's switching problem 4) Do we need AI agents? 5) Thinking Vs. Doing AI 6) Sam Altman says parts of AI are a bubble 7) Eric Schmidt says the U.S. should stop overindexing on AGI and instead build it into products 8) GPT-6 is going to have much better memory 9) MIT study says 95% of AI projects fail to achieve their goals 10) AI may replace OnlyFans outsourced 'chatters' 11) Is love AI's real use case? --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Nick Fox is the SVP of Knowledge and Information at Google. Liz Reid is the VP of Search at Google. The two join Big Technology Podcast to discuss the way Google plans and builds in the generative AI era, including how it chooses what to ship and when. We also cover publisher traffic, search monetization and ads, shopping and product research, and the near-term future of the web. Hit play for a clear, no-fluff conversation with the leaders building search’s next chapter. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Matthew Prince is the CEO of Cloudflare. He joins Big Technology podcast to discuss whether the web can withstand a wave of generative AI companies scraping content, summarizing it, and not cutting the original creators into the revenue. Tune in to hear Prince masterfully dissect the problem and put forth a solution.

Anthony Aguirre is the executive director of the Future of Life Institute. He joins Big Technology to discuss how AI could fail in the worst case and whether our push toward increasingly autonomous, general systems puts control out of reach. Tune in to hear how agentic systems operating at superhuman speed complicate oversight, and why “just unplug it” is naive. Hit play for a cool‑headed, nuanced conversation with clear takeaways you can use to evaluate AI strategy, policy, and risk. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) OpenAI's launch of GPT-5 2) Whether GPT-5's tool calling ability is its hidden strength 3) GPT-5 is good at 'doing stuff' 4) But GPT-5 is not AGI 5) Do AI models need more than book smarts to thrive? 6) OpenAI's medicine play 7) GPT-5's coding use case 8) We need AI tables for travel 9) Do the big model players now subsume AI startups? 10) Gemini has a breakdown --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Brad Lightcap is the Chief Operating Officer of OpenAI. Lightcap joins Big Technology to discuss the launch of GPT-5, how it works, what sets it apart from previous models, and whether it's AGI. We also cover scaling laws, post-training breakthroughs, enterprise adoption, health care applications, pricing strategy, and the company’s profitability outlook. Hit play for a front-row seat to OpenAI’s thinking on the future of AI. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Amjad Masad is the CEO of Replit. Masad joins Big Technology podcast for a frank discussion about vibe coding, or building software via prompt. We discuss all the use cases, whether anyone can do it or whether it's just a tool for already-technical builders, whether vibe coding replaces saas, and what the role of the engineer becomes in the future. Stay tuned for the second half where we discuss whether the AI coding business is sustainable given the costs of delivering the technology. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

M.G. Siegler is the author of Spyglass. He joins Big Technology podcast for the latest of our first Monday of the month discussion about Big Tech strategy and AI. Today we cover Mark Zuckerberg's vision for personal superintelligence and whether it's more of a recruiting play or a real difference in the way the company builds AI. We also cover the massive bets on AI and whether they'll ever pay off, how interlinked big tech is with AI, and whether you should outsource your writing to AI. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Alex's profile of Anthropic CEO Dario Amodei + extra reporting 2) Are Anthropic's convictions earnest or marketing? 3) Where does Anthropic fit in the broader AI landscape 4) Will one AI company 'win it all' 5) Anthropic is raising at a new, $170 billion valuation 6) OpenAI hits 700 million ChatGPT users 7) Hyped for GPT-5? 8) AI video creation's promise 9) Videos in Google's NotebookLM 10) Is the stock market in a bubble or hitting real returns. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com