TWiM describes a potential connection between a bacterial protein that damages DNA, and human cancers, and how to synthesize antimicrobial natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

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• Colorectal cancer and E. coli (Nature)
• Natural products from ancient bacterial genomes (Science)
• Underexplored bacteria reservoirs of antimicrobial lipopeptides (Front Chem)
• Fries With That Mammoth Burger? (Mother Jones)
• 25-40 million year old spores (Science)
• 250 million year old bacterium from salt crystal (Nature)
• 1918 influenza with Jeffery Taubenberger (TWiV 966)
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Music used on TWiM is by Ronald Jenkees

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv