When Portuguese neurologist Egas Moniz developed the lobotomy in 1935, it was little more than a crude surgery developed as a blanket treatment for mental illness that involved drilling into the skull and scrambling the neural connections in the frontal lobe. Less than a decade later, however, American neurologist Walter Jackson Freeman had refined Moniz’s procedure and developed a non-surgical procedure that could be performed in a doctor’s office, which he called a transorbital lobotomy. What he touted as successes, quickly turned into a series of life altering failures...but he kept going.

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