Ira Glass talks with Nancy Updike about the most personal stories they have put on the radio.

864: Chicago Hope

Each week we choose a theme. Then anything can happen. This American Life is true stories that unfold like little movies for radio. Personal stories with funny moments, big feelings, and surprising plot twists. Newsy stories that try to capture what it’s like to be alive right now. It’s the most popular weekly podcast in the world, and winner of the first ever Pulitzer Prize for a radio show or podcast. Hosted by Ira Glass and produced in collaboration with WBEZ Chicago.