A review of randomized control trials of at least 24-month duration. 00:45 There are nutrients/vitamins in fat. 01:30 There was little or no effect on cardiovascular or all-cause mortality by reducing saturated fat for 2 years. 01:38 Reducing saturated fat possibly reduced cardiovascular events. 04:00 Heart attack risk and saturated fat reduction has no clear correlation. 05:30 Replacing saturated fat with polyunsaturated or monounsaturated fat, carbs, or protein effects did not differ. 06:15 There may be a prevention of second heart attacks with saturated fat reduction. 07:00 Other cardiovascular events and cancer outcomes effects were very small or unclear. 08:00 Carbohydrates and processed foods are often used to replace saturated fat in the diet.